Description

PE-22-28 is a synthetic peptide fragment derived from the spadin sequence, engineered for targeted laboratory investigation of neurotrophic and ion channel–associated signaling pathways. In controlled research environments, PE-22-28 is studied for its interaction with TREK-1 (TWIK-related potassium channel-1) and related neuronal membrane activity mechanisms.

TREK-1 channels play a role in regulating neuronal excitability and cellular stress response pathways. In preclinical and in vitro research models, PE-22-28 is frequently utilized to explore:

TREK-1 channel modulation studies

Neurotrophic signaling pathway analysis

Neuronal excitability modeling

Ion channel interaction research

Cellular stress response investigations

Due to its fragment-based structure and defined target interaction profile, PE-22-28 is relevant in advanced neuroscience research frameworks focused on membrane channel dynamics and peptide-mediated signaling.

Supplied in lyophilized form to ensure stability and reproducibility under laboratory conditions.

Strictly intended for laboratory research use only. Not for human or veterinary use.