kpv research peptide
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KPV

$80.00

In Stock
KPV is studied for its potential anti-inflammatory effects and its role in modulating immune responses. Derived from an α-MSH fragment, it may help regulate inflammatory pathways and support gut and skin health. Researchers explore its applications in conditions where immune modulation is a primary focus.

In stock

Quantity Discount (%) Price
1 $80.00
3 12.5 % $70.00
6 18.75 % $65.00
12+ 25 % $60.00

99%+ Purity Tests

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Free bacteriostatic water with every order.

Overview

Research indicates that KPV may help modulate inflammation throughout the body. This compact tripeptide, derived from a natural hormone, has gained interest for its potential to support gut health, aid skin repair, and reduce inflammatory responses. Studies suggest it acts by inhibiting cellular pathways that trigger inflammation. Researchers are investigating its applications for both digestive health and skin-related conditions.

Use our Research Peptide Storage Guide — Laboratory Use Only — to ensure proper handling and stability for controlled experimental applications. Not for human consumption, therapeutic, or diagnostic use.

Key Characteristics

Molecular Details

  • Chemical Formula: C₁₆H₂₁N₃O₅

  • Molecular Weight: ~339.35 g/mol

  • CAS Number: 137388-70-2

  • Structure: Tripeptide derived from α-MSH with potent anti-inflammatory signaling activity

Product Information

  • Form: Lyophilized powder

  • Solubility: Soluble in sterile water or aqueous buffers

  • Stability: Stable when frozen; limited stability after reconstitution

  • Half-Life: Short systemic half-life; rapidly metabolized in vivo

  • Storage: Store refrigerated at 36–46°F (2–8°C); protect from light and moisture

How It Works

A melanocortin-derived tripeptide researched for its anti-inflammatory properties, immune modulation effects, and support of gut and tissue homeostasis.

Primary Mechanisms

Anti-Inflammatory Signaling Modulation

Reduces pro-inflammatory cytokine expression and dampens excessive inflammatory responses

Melanocortin Pathway Interaction

Derived from α-MSH signaling pathways and influences immune-regulatory mechanisms

Immune Response Regulation

Supports balanced immune activation while limiting excessive inflammatory damage

Gut Barrier & Tissue Protection

Enhances epithelial integrity and protects mucosal tissues in research models

Research Benefits

Inflammation Reduction Studies

Investigated for decreasing inflammatory markers in gut and systemic tissue models

Gastrointestinal Support Research

Studied for improving intestinal barrier function and reducing inflammatory bowel pathology markers

Skin & Tissue Repair Research

Explored for reducing inflammatory damage and supporting tissue healing responses

Immune Modulation Effects

Evaluated for balancing immune signaling during acute and chronic inflammatory conditions

Research Findings

Laboratory investigations have provided valuable insights into CJC-1295’s biological activity and research applications.

Gastrointestinal Benefits

Studies demonstrate strong effects in intestinal inflammation models:

  • Reduces inflammatory markers in IBD models

  • Protects against epithelial barrier disruption

  • Improves mucosal healing and tissue regeneration

  • Enhances tripeptide uptake via PepT1 transport mechanisms

Anti-Inflammatory Activit

Research indicates measurable modulation of inflammatory pathways:

  • Decreases TNF-α and other pro-inflammatory cytokines

  • Reduces oxidative stress in tissue injury models

  • Supports immune-mediated inflammation control

  • Demonstrates protective effects in colitis and gut injury studies

Microbiome & Barrier Function

Studies indicate KPV supports gut health beyond inflammation control:

  • Promotes beneficial gut microbiota balance in experimental colitis models

  • Enhances tight junction protein expression to strengthen epithelial barriers

Metabolic ResearchSystemic Inflammatory Modulation

Research suggests broader immune effects:

  • Reduces systemic inflammatory signaling in whole-organism models

  • Supports resolution of inflammation in multiple tissue injury contexts

Potential Side Effects in Research

Safety considerations and tolerability profile observed in research settings.

Generally Well Tolerated

KPV has demonstrated favorable tolerability in preclinical research

Minimal Adverse Effects

Few significant side effects reported at studied doses.

Injection Site Reactions

Possible mild, temporary irritation at administration sites.

Limited Long-Term Human Data

Most safety data comes from animal and early-stage research models.

These effects appear to be dose-dependent and generally resolve after the peptide’s active period.

References

THIRD-PARTY LAB TESTED

Certificate of Analysis

Independent laboratory testing confirms purity and composition

99.145%

Purity

62ABF

Batch

December 2026

Date

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